The Owyhee flows from the Owyhee Reservoir in eastern Oregon to the Oregon/Idaho state border through mostly remote, arid, and undeveloped land. Much of the river travels through incised canyons that are home to mountain lions, bobcats, mule deer, golden eagles, and big horn sheep. The North Fork of the river, in the high plateau region of southeast Oregon, is provides for expert kayaking in an extremely remote environment.